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Molecular Biology products

Delivering complete PCR solutions for Molecular Biology Research

SHARD DIAGNOSTICS™ Molecular Biology qPCR assays streamline gene expression analysis, SNP genotyping, variant detection, and target quantification, helping you move from sample to result faster, while maintaining exceptional performance. Choose ready-to-use human assays or request a custom design for your organism of interest.

SHARD DIAGNOSTICS™ kit features

Each kit features lyophilized inhibitor-tolerant reagents that deliver consistent amplification even from challenging or impure samples, effectively eliminating performance variability caused by the sample or extraction process. The universal chemistry supports all targets using a standardized cycling protocol, allowing multiple assays to run on the same 96-well plate. Quantified positive controls are included to standardise run performance across machines and provide quality control measures.

Solutions not just kits

Universal cycling & commonly used fluorophores utilised for fast integration.

Complete kits

Quantified controls included as standard for all targets including RNA and mutations.

Advanced performance

Extraction-free for RNA and DNA. Target detection down to 0.001% VAF or 3 copies.

Available globally

All reagents are lyophilized for ambient shipping and inhibitor-tolerant as standard.

Launch Program Definitions

The shard-dx™ product launch pathway allows customers to access the technology earlier with exciting rewards.

PRE-LAUNCH >

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Development status: Product initiated for development via established shard-dx™ technology.
Pre-launch program: Join the shard-dx™ pre-launch access program to generate cutting-edge kits alongside us. The program provides customers early access to upcoming kits, opportunities for free of charge customisation and a 12-month 20% discount on the kit upon official ‘AVAILABLE (RUO)’ launch [max 25 x 96 reaction kits]. Additionally, a 15% discount will be available for pre-launch access customers on all shard-dx™ products [discounts cannot be combined, max 10 orders]. Find out more about the pre-launch program by emailing info@shard-dx.com. Pre-launch program access terms and conditions apply.

ALPHA LAUNCH >

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Development status: Product initiated for development via established shard-dx™ technology. In-silico and proof-of-concept wet-lab development undertaken.
Alpha launch program: Join the shard-dx™ alpha access program to generate cutting-edge kits alongside us. The program provides customers early access to upcoming kits, opportunities for free of charge customisation and a 12-month 20% discount on the kit upon official ‘AVAILABLE (RUO)’ launch [max 15 x 96 reaction kits]. Additionally, a 15% discount will be available for alpha access customers on all shard-dx™ products [discounts cannot be combined, max 7 orders]. Find out more about the alpha program by emailing info@shard-dx.com. Alpha program access terms and conditions apply.

BETA LAUNCH >

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Development status: Near finished product via established shard-dx™ technology. Wet-lab development with significant optimisation undertaken.
BETA launch program: Join the shard-dx™ beta access program to generate cutting-edge kits alongside us. The program provides customers early access to kits launching soon, opportunities for free of charge customisation and a 12-month 20% discount on the kit upon official ‘AVAILABLE (RUO)’ launch [max 10 x 96 reaction kits]. Additionally, a 10% discount will be available for beta access customers on all shard-dx™ products [discounts cannot be combined, max 5 orders]. Find out more about the beta program by emailing info@shard-dx.com. Beta program access terms and conditions apply.

AVAILABLE (RUO) >

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Development status: Product is an established Research Use Only (RUO) kit.
SHARD DIAGNOSTICS™ Quality Management System (QMS) status: Internal QMS operational. Preparation phase for ISO9001 & ISO13485. External manufacturing of complete kits under GMP and/or ISO13485 is available and can be organised by shard-dx™.
Additional options: Kit can be customised at a reduced cost to the customer compared with a stand alone custom kit. Additional sample, workflow and automation validation for the kit may be available at a reduced cost to the customer compared with stand alone custom kits.

AVAILABLE (CE-IVD or FDA)

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Development status: Product is an established CE-IVD or FDA-cleared kit.
SHARD DIAGNOSTICS™ Quality Management System (QMS) status: Internal QMS operational. Preparation phase for ISO9001 & ISO13485. External manufacturing of complete kits under GMP and/or ISO13485 is available and can be organised by shard-dx™.
Additional options: Kit can be customised at a reduced cost to the customer compared with a stand alone custom kit. Additional sample, workflow and automation validation for the kit may be available at a reduced cost to the customer compared with stand alone custom kits.

Custom Molecular Biology kits

AVAILABLE (RUO): Custom qPCR kits

Find out more about custom PCR kits on our dedicated pages.
Format: Lyophilized inhibitor-tolerant qPCR or 1-step RT-qPCR.
Applications: Variant detection (DNA and/or RNA), gene expression, target quantification, target qualitative detection, extraction-free, rapid detection and cartridge-based system integration.
Targets: Singleplex or multiplex.
Detection method: Probe.
Shipping: Ambient.
Positive control inclusion: Yes.
Regulatory status: Research Use Only (RUO).
Sample type: Flexible (DNA, RNA or DNA/RNA combined).
Product code (SKU): SDCA_CUSTOMER LAST NAME_ORDER NUMBER.

BETA LAUNCH (RUO): Custom dPCR kits

Find out more about custom PCR kits on our dedicated pages.
Format: Lyophilized inhibitor-tolerant dPCR or 1-step RT-dPCR.
Applications: Variant detection, gene expression and target quantification.
Targets: Singleplex or multiplex.
Detection method: Probe.
Shipping: Ambient.
Positive control inclusion: Yes.
Regulatory status: Research Use Only (RUO).
Sample type: Flexible (DNA, RNA or DNA/RNA combined).
Development status: Beta launch. Ongoing validation with established shard-dx™ platforms.
BETA launch program: Join the shard-dx™ beta access program to generate cutting-edge kits alongside us. Find out more on the launch programs definition section on each custom page and product page.
Product code (SKU): SDCA_CUSTOMER LAST NAME_ORDER NUMBER.

PRE-LAUNCH (RUO): Custom amplicon sequencing kit

Find out more about custom PCR kits on our dedicated pages.
Format: Lyophilized inhibitor-tolerant PCR or 1-step RT-PCR.
Applications: Variant detection, gene expression, target qualitative detection and extraction-free.
Targets: Multiplex, long and short read.
Sample type: Flexible (DNA, RNA or DNA/RNA combined).
Shipping: Ambient.
Positive control inclusion: Yes.
Development status: Pre-launch. Ongoing research and development with established lyophilized inhibitor tolerant shard-dx™ platforms.
Regulatory status: Research Use Only (RUO).
Pre-launch program: Join the shard-dx™ pre-launch program to generate cutting-edge kits alongside us. Find out more on the launch programs definition section on each custom page and product page.
Product code (SKU): SDCA_CUSTOMER LAST NAME_ORDER NUMBER.

Molecular biology kits (qPCR) - general

PRE-LAUNCH: NGS library quantification kit

Product name: LyoMorph-Q NGS quantification kit
Product code (SKU): SD_HMB_00030
Format: qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Quantification of NGS libraries may be useful at multiple preparation stages as a quality control step prior to sequencing.
Development status: Pre-launch. Product initiated for development via established shard-dx™ technology. In-silico development undertaken.
Targets:
- Common adapter-ligated sequences such as P5/P7 (FAM)
Limit of Detection - copies (95%): ≤10 planned
Detection method: Probe
Sample type: DNA
Reactions: 96/1000
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)
Pre-launch program: Join the shard-dx™ pre-launch program to generate cutting-edge kits alongside us. Find out more on the launch programs definition section on each custom page and product page.

Molecular biology kits (qPCR) - human

AVAILABLE (RUO): Beta-2-Microglobulin (B2M) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ B2M expression kit
Product code (SKU): SD_HMB_00031
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: To normalise RNA gene expression in RT-qPCR as a housekeeping assay. To act as an internal control to determine reliable run-to-run amplification. To act as an internal control to determine the presence of human RNA in a sample.
Target: B2M
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 96/1000
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): BCL2 Associated X Protein (BAX) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ BAX expression kit
Product code (SKU): SD_HMB_00015
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of BAX gene expression changes may play a role in apoptosis among other abnormal or normal cellular processes.
Target: BAX
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): BCL2 apoptosis regulator (BCL2) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ BCL2 expression kit
Product code (SKU): SD_HMB_00014
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of BCL2 gene expression changes may play a role in apoptosis among other abnormal or normal cellular processes.
Target: BCL2
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Cyclin D1 (CCND1) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ CCND1 expression kit
Product code (SKU): SD_HMB_00012
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of CCND1 gene expression changes may play a role in proliferation among other abnormal or normal cellular processes.
Target: CCND1
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Programmed Cell Death Ligand 1 (CD274) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ CD274 expression kit
Product code (SKU): SD_HMB_00024
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of CD274 gene expression changes may play a role immune cell regulation among other abnormal or normal cellular processes.
Target: CD274
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): E-Cadherin (CDH1) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ CDH1 expression kit
Product code (SKU): SD_HMB_00016
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of CDH1 gene expression changes may play a role in epithelial-mesenchymal transition among other abnormal or normal cellular processes.
Target: CDH1
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Hypoxia Inducible Factor 1 Subunit Alpha (HIF1A) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ HIF1A expression kit
Product code (SKU): SD_HMB_00023
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of HIF1A gene expression changes may play a role in angiogenesis among other abnormal or normal cellular processes.
Target: HIF1A
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Interleukin 6 (IL-6) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ IL-6 expression kit
Product code (SKU): SD_HMB_00001
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of IL6 gene expression changes may play a role in inflammation among other abnormal or normal cellular processes.
Target: IL-6
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Marker Of Proliferation Ki-67 (KI-67) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ KI-67 expression kit
Product code (SKU): SD_HMB_00011
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of KI-67 gene expression changes may play a role in proliferation among other abnormal or normal cellular processes.
Target: KI-67
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): MYC Proto-Oncogene, BHLH Transcription Factor (MYC) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ MYC expression kit
Product code (SKU): SD_HMB_00013
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of MYC gene expression changes may play a role in proliferation among other abnormal or normal cellular processes.
Target: MYC
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Snail Family Transcriptional Repressor 1 (SNAI1) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ SNAI1 expression kit
Product code (SKU): SD_HMB_00019
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of SNAI1 gene expression changes may play a role in epithelial-mesenchymal transition among other abnormal or normal cellular processes.
Target: SNAI1
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Transforming Growth Factor Beta 2 (TGFB2) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ TGFB2 expression kit
Product code (SKU): SD_HMB_00026
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of TGFB2 gene expression changes may play a role in inflammation among other abnormal or normal cellular processes.
Target: TGFB2
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Tumor Necrosis Factor-Alpha (TNFA) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ TNFA expression kit
Product code (SKU): SD_HMB_00002
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of TNFA gene expression changes may play a role in inflammation and autoimmunity among other abnormal or normal cellular processes.
Target: TNFA
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Tumor Protein P53 (TP53) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ TP53 expression kit
Product code (SKU): SD_HMB_00009
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of TP53 gene expression changes may play a role in DNA damage sensing/repair and cell cycle activity among other abnormal or normal cellular processes.
Target: TP53
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Vascular Endothelial Growth Factor A (VEGFA) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ VEGFA expression kit
Product code (SKU): SD_HMB_00005
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of VEGFA gene expression changes may play a role in angiogenesis among other abnormal or normal cellular processes.
Target: VEGFA
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Vimentin (VIM) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ VIM expression kit
Product code (SKU): SD_HMB_00018
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of VIM gene expression changes may play a role in epithelial-mesenchymal transition among other abnormal or normal cellular processes.
Target: VIM
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

AVAILABLE (RUO): Zinc Finger E-Box Binding Homeobox 1 (ZEB1) 1-step RT-qPCR gene expression assay

Product name: LyoMorph-RTQ ZEB1 expression kit
Product code (SKU): SD_HMB_00020
Format: 1-step RT-qPCR - lyophilized and inhibitor-tolerant
Potential use cases: Detection or quantification of ZEB1 gene expression changes may play a role in epithelial-mesenchymal transition among other abnormal or normal cellular processes.
Target: ZEB1
Efficiency: 90-110%
Detection method: Probe
Sample type: RNA
Reactions: 48
Shipping: Ambient
Number of mastermixes: 1
Number of reactions required per sample: 1
Positive control inclusion: Yes
Regulatory status: Research Use Only (RUO)

Didn't find your target or configuration? Try custom.

Custom: Express PCR kits

Low scale (96 reactions) to high scale lyophilized inhibitor tolerant qPCR and 1-step RT-qPCR kits for your target.

Custom: OEM/White-label kits

License from us to gain an edge over the competition with industry-leading performance. Available in your branding.

Custom: Academic collaborations

Collaborate with shard-dx™ to gain access to our innovative technology and support for rapid progression together.

Custom: Clinically focused applications

Your clinical application combined with our technology, completely custom with the option for extensive performance testing.

Request a quote or consultation

Information

Products

Custom Kits

Contact Us

Location:

BioCity Nottingham, Pennyfoot Street, Nottingham, England, NG1 1GF

Email:

info@shard-dx.com

Molecular Biology products

Delivering complete PCR solutions for Molecular Biology Research

SHARD DIAGNOSTICS™ kit features

Solutions not just kits

Complete kits

Advanced performance

Available globally

Molecular biology kits (qPCR) - general

Molecular biology kits (qPCR) - human

Custom: Express PCR kits

Custom: OEM/White-label kits

Custom: Academic collaborations

Custom: Clinically focused applications

Request a quote or consultation

Information

Products

Custom Kits

Contact Us

UK. Registered No 15798577SHARD DIAGNOSTICS™ and shard-dx™ are trademarks of SHARD DIAGNOSTICS LTD. All rights reserved.

UK. Registered No 15798577

SHARD DIAGNOSTICS™ and shard-dx™ are trademarks of SHARD DIAGNOSTICS LTD. All rights reserved.